Aurigene Oncology Limited has released encouraging initial results from the first two cohorts of its Phase 1 trial of AUR112, an oral small molecule inhibitor of MALT1, in patients with relapsed/refractory lymphoid malignancies. Early findings show the drug is safe, well tolerated, and demonstrates meaningful clinical activity across lymphoma subtypes.
Aurigene Oncology Limited, a clinical-stage biopharmaceutical company focused on novel cancer therapies, announced initial data from the first two cohorts of its ongoing Phase 1 study of AUR112. The trial evaluates AUR112 in patients with relapsed or refractory lymphoid malignancies, including Mantle Cell Lymphoma (MCL) and Marginal Zone Lymphoma (MZL).
According to the company, AUR112 has shown a favorable safety profile and was well tolerated, with objective responses observed across multiple lymphoma subtypes. These early results highlight the potential of AUR112 as a targeted therapy for patients who have limited treatment options.
The study continues to enroll additional cohorts, with further updates expected as more data becomes available. Aurigene’s progress underscores its commitment to advancing innovative oncology treatments in India and globally.
Key Highlights / Major Takeaways
Drug Candidate: AUR112, oral small molecule inhibitor of MALT1.
Trial Stage: Phase 1, first two cohorts completed.
Patient Group: Relapsed/refractory lymphoid malignancies (MCL, MZL).
Safety Profile: Drug found safe and well tolerated.
Clinical Activity: Objective responses observed across lymphoma subtypes.
Next Steps: Continued enrollment and expanded data readouts expected.
Sources: FinancialContent – BusinessWire Release, GuruFocus.