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When Kidney Health Meets Nighttime Restlessness: Unraveling the Mystery of Restless Legs Syndrome


Updated: June 21, 2025 02:00

Image Source: Times Of India
Restless Legs Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological condition causing an uncontrollable urge to move the legs, often due to uncomfortable sensations like itching, crawling, or throbbing. Symptoms typically worsen at night or during periods of rest, disrupting sleep and daily life. RLS can be linked to kidney problems, as impaired kidney function may trigger or worsen symptoms.
 
Key Highlights:
 
RLS sensations usually begin when resting or lying down and improve temporarily with movement such as walking or stretching.
Causes include iron deficiency, nerve damage, diabetes, pregnancy, and notably, kidney failure or chronic kidney disease, which can cause toxin buildup affecting nerves.
Diagnosis involves symptom review, medical history, neurological exams, and blood tests to rule out iron deficiency or kidney issues.
Treatments focus on lifestyle changes—regular exercise, avoiding caffeine and alcohol, leg massages, and maintaining a sleep routine.
Medications may include iron supplements, anti-seizure drugs, or dopaminergic agents; new FDA-approved devices like tonic motor activation (TOMAC) can also reduce symptoms.
Managing underlying kidney health is crucial to alleviating RLS symptoms linked to renal dysfunction.
 
Outlook:
 
While RLS has no cure, early diagnosis and a combination of lifestyle adjustments, medical treatment, and kidney care can significantly improve quality of life and sleep for sufferers.
 
Source: Mayo Clinic, Cleveland Clinic, NIH, Johns Hopkins Medicine

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