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Glenmark’s IGI Strikes $1.9 Billion Global Licensing Deal with AbbVie for Cancer Drug ISB 2001

Updated: July 10, 2025 17:35

Image Source : The Hindu Business Line
Glenmark Pharmaceuticals’ biotech arm, Ichnos Glenmark Innovation (IGI), has signed an exclusive global licensing agreement with AbbVie for its lead investigational asset, ISB 2001—a first-in-class trispecific antibody targeting multiple myeloma.
 
Key Highlights
  • - IGI will receive an upfront payment of USD 700 million and is eligible for up to USD 1.225 billion in milestone payments.
  • - AbbVie gains exclusive rights to develop, manufacture, and commercialize ISB 2001 across North America, Europe, Japan, and Greater China.
  • - IGI will also earn tiered, double-digit royalties on net sales.
  • Drug Profile
  • - ISB 2001 is a trispecific T-cell engager targeting BCMA, CD38, and CD3, currently in Phase 1 trials for relapsed/refractory multiple myeloma.
  • - Developed using IGI’s proprietary BEAT protein platform, the drug has shown a 79% overall response rate in early trials.
Strategic Impact
- The deal marks a major milestone for Glenmark’s innovation pipeline and positions IGI as a global player in immuno-oncology.
 
Sources: GlobeNewswire, CNBC TV18, Rediff Money, IGInnovate.com, Economic Times, The Hindu Business Line

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